Sexual health has attained greater acceptance as a field of study. This shift is reflected in the recent increase in various pharmacological treatments for sexual dysfunctions among men and women. In this context, greater attention is now being devoted to improving self-report sexual health assessment methods in health surveys. A central problem in this respect is that that sexual dysfunctions are socially stigmatized and, therefore, difficult or impossible to for some people to discuss. Although past studies have examined methods for improving self-reports of sexual behavior little of this work has concerned sexual dysfunctions. We examine the effects of mode of administration (CASI, ACASI, CAPI) on assessments of erectile and ejaculatory dysfunction in older men, and the moderating effects of age, social desirability, and mood on these relationships. We conducted a randomized experiment (N = 249) of men over age 50 years. In logistic regression models, we found that mode had no effect in the ejaculation model, but two significant interactions with mode occurred in the erection model: Age x Mode (p = .04), and social desirability x Mode (p = .02). The results were not typical in that more stigmatized behavior was reported with CAPI and ACASI, but not CASI and age and social desirability effects were more prominent under CASI. The results are discussed in terms of social support theory in the context of reporting sensitive health problems, threat to selfesteem, and order effects. In sum, the results suggest that ACASI and CAPI are reasonable options to offer men in assessing erectile dysfunction in sexual health surveys.